Relationship between cognitive, physiological and functional variability and neuropathology Lead Investigator: Channing Sofko Institution : University of South Alabama E-Mail : cas1325@jagmail.southalabama.edu Proposal ID : 442 Proposal Description: The purpose of the proposed study is two-fold the first is to assess through structural equation modeling how measures of cognitive, physiological, and functional intra-individual variability relate to an underlying latent construct. The second purpose is to determine how this latent construct is related to neuropathology at time of death.